Ashleigh R Poh Selected Research

AZD4320

5/2021

A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma.

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Ashleigh R Poh Research Topics

Disease

15	Neoplasms (Cancer) 01/2024 - 09/2014
4	Colonic Neoplasms (Colon Cancer) 04/2024 - 09/2014
4	Stomach Neoplasms (Stomach Cancer) 01/2024 - 07/2016
3	Carcinogenesis 10/2023 - 09/2014
1	Disease Progression 04/2024
1	Colorectal Neoplasms (Colorectal Cancer) 04/2024
1	Hyperplasia 10/2023
1	Metaplasia 10/2023
1	Adenocarcinoma 10/2022
1	Malignant Mesothelioma 05/2021
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2019
1	Osteoporosis 01/2019
1	Intestinal Neoplasms (Intestinal Cancer) 01/2019
1	Hematologic Neoplasms (Hematological Malignancy) 10/2017
1	Leukemia 06/2015
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 09/2014
1	Inflammation (Inflammations) 05/2014

Drug/Important Bio-Agent (IBA)

7	CytokinesIBA 01/2024 - 09/2014
4	Proto-Oncogene Proteins c-hckIBA 06/2022 - 06/2015
3	Interleukin-11 (Interleukin 11)IBA 04/2024 - 01/2019
3	Interleukin-6 (Interleukin 6)IBA 04/2024 - 01/2019
3	src-Family KinasesIBA 06/2022 - 10/2017
2	Proteins (Proteins, Gene)FDA Link 04/2024 - 06/2015
2	bazedoxifeneIBA 04/2024 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2018
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020 - 09/2014
2	CateninsIBA 01/2019 - 09/2014
2	InterleukinsIBA 01/2019 - 01/2019
2	Interleukin-33IBA 01/2019 - 05/2014
2	Phosphotransferases (Kinase)IBA 06/2015 - 09/2014
1	LCL161IBA 04/2024
1	birinapantIBA 04/2024
1	Interleukin-17 (Interleukin 17)IBA 10/2023
1	Interleukin-13IBA 10/2023
1	Oncogene Proteins (Oncogene Protein)IBA 12/2022
1	Programmed Cell Death 1 ReceptorIBA 06/2022
1	Lysine (L-Lysine)FDA Link 05/2021
1	AZD0466IBA 05/2021
1	Cisplatin (Platino)FDA LinkGeneric 05/2021
1	AZD5991IBA 05/2021
1	Pemetrexed (MTA)FDA Link 05/2021
1	Dendrimers (Dendrons)IBA 05/2021
1	AZD4320IBA 05/2021
1	MucinsIBA 01/2020
1	SteroidsIBA 01/2019
1	AlarminsIBA 01/2019
1	Selective Estrogen Receptor Modulators (SERM)IBA 01/2019
1	Complement System Proteins (Complement)IBA 01/2018
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2015
1	tyrosine receptor (receptor, tyrosine)IBA 06/2015
1	Janus KinasesIBA 09/2014
1	Type I Tumor Necrosis Factor ReceptorsIBA 05/2014

Therapy/Procedure

6	Therapeutics 12/2023 - 07/2016
2	Drug Therapy (Chemotherapy) 04/2024 - 05/2021
1	Splenectomy 01/2023
1	Immunotherapy 06/2022